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Godina je 1979. i u jednoj njujorškoj bolnici na Menhetnu se rodila djevojčica. Istog dana, mladi sveštenik na nebu primjećuje lučnu putanju komete iznad mjeseca (što je u filmu opisano kao "Božije Oko"), i o toj pojavi obavještava Papu. Katolička crkva već vjekovima strahuje od ovog događaja, a njihovi strahovi se potvrđuju kada se otkrije da novorođena djevojčica imenom Kristina, na tijelu nosi obilježje Antihrista The year is 1979 and a girl was born in a New York hospital in Manhattan. That same day, a young priest in the sky notices an arcing path of a comet above the moon (described in the movie as the "Eye of God"), and informs the Pope about the phenomenon. The Catholic Church has been afraid of this event for centuries, and their fears are confirmed when it is discovered that a newborn girl named Cristine bears the mark of the Antichrist on her body.

Njujork, 28.12.1999. Ljudi se spremaju za dolazak novog milenijuma. Džeriko Kejn, suicidalni bivši policajac i alkoholičar, depresivan nakon ugovorenog ubistva njegove supruge i kćerke, radi za privatnu sigurnosnu kompaniju i krivi Boga za njegovu patnju. Zajedno sa partnerom Bobijem Čikagom radi kao obezbjeđenje bankara, u čije je tjelo ušao Đavo New York, 28.12.1999. People are preparing for the arrival of the new millennium. Jericho Kane, a suicidal ex-cop and alcoholic, depressed after the contract killing of his wife and daughter, works for a private security company and blames God for his suffering. Together with his partner Bobby Chicago, he works as security for a banker, whose body is possessed by Satan.

Jednom prilikom, Džeriko uspije spasiti mladu ženu od napadača koji su joj provalili u dom. Uskoro donaznaje da se zove Kristina, te da cijeloga života pati od uznemirujućih vizija koja je progone. Uoči dočeka Nove godine te vizije su se pretvorile u jezivu javu. Proganja je tajanstveni muškarac, utjelovljenje samog Đavola, a jedini koji joj može pomoći je Kejn koji je odavno izgubio vjeru On one occasion, Jericho manages to save a young woman from attackers who broke into her home. Soon he finds out that her name is Christine, and that she has been suffering from disturbing visions that haunt her all her life. On the eve of New Year's Eve, those visions turned into a terrifying reality. She is being chased by a mysterious man, the embodiment of the Devil himself, and the only one who can help her is Kane, who lost his faith a long time ago.